Publications

  1. Daniel Aberdam, the legacy of a mentor. Zhou H, Attali B, Lagali N, Shalom-Feuerstein R. Cell Death & Differentiation 2025
  2. HMCN1 variants aggravate epidermolysis bullosa simplex phenotype. Bergson S, Sarig O… Shalom-Feuerstein R, Wally V, Koller U, Samuelov L, Haitin Y, Ashery U, Rubinstein R, Sprecher E. Journal of Experimental Medicine 2025
  3. miR-184 represses β-catenin and behaves as a skin tumor suppressor. Lubov Turovsky, Ghazal Kheshaiboun, Gharam Yassen, Sara Nagossa, Ilanit Boyango, Swarnabh Bhattacharya, Neta Ilan, Israel Vlodavsky, Daniel Aberdam, Ruby Shalom Feuerstein and Emily Avitan-Hersh. Cell Death & Disease 2024
  4. miR-200b-mediated reversion of a spectrum of epithelial to mesenchymal transition states in recessive dystrophic epidermolysis bullosa squamous cell carcinomas. Illmer J, Zauner R, Piñón Hofbauer J, Wimmer M, Gruner S, Ablinger M, Bischof J, Dorfer S, Hainzl S, Tober V, Bergson S, Sarig O, Samuelov L, Guttmann-Gruber C, Shalom-Feuerstein R, Sprecher E, Koller U, Laimer M, Bauer JW, Wally V. British Journal of Dermatology 2023
  5. Eyes open on stem cells. Altshuler A, Amitai-Lange A, Nasser W, Dimri S, Bhattacharya S, Tiosano B, Barbara R, Aberdam D, Shimmura S, Shalom-Feuerstein R. Stem Cell Reports 2023
  6. The biophysical property of the limbal niche maintains stemness through YAP. Bhattacharya S, Mukherjee A, Pisano S, Dimri S, Knaane E, Altshuler A, Nasser W, Dey S, Shi L, Mizrahi I, Blum N, Jokel O, Amitai-Lange A, Kaganovsky A, Mimouni M, Socea S, Midlij M, Tiosano B, Hasson P, Feral C, Wolfenson H, Shalom-Feuerstein R. Cell Death & Differerentiation 2023
  7. Spotlighting adult stem cells: advances, pitfalls, and challenges. Altshuler A, Wickström SA, Shalom-Feuerstein R. Trends in Cell Biology 2022
  8. Thy1 marks a distinct population of slow-cycling stem cells in the mouse epidermis. Koren E, Feldman A, Yusupova M, Kadosh A, Sedov E, Ankawa R, Yosefzon Y, Nasser W, Gerstberger S, Kimel LB, Priselac N, Brown S, Sharma S, Gorenc T, Shalom-Feuerstein R, Steller H, Shemesh T, Fuchs Y. Nature Communication 2022
  9. Stem cell responses to stretch and strain. Bhattacharya S, Wolfenson H, Shivdasani R, Shalom-Feuerstein R. Trends in Cell Biology 2021 
  10. Pathophysiology of aniridia-associated keratopathy: Developmental aspects and unanswered questions. Latta L, Figueiredo FC, Ashery-Padan R, Collinson JM, Daniels J, Ferrari S, Szentmáry N, Solá S, Shalom-Feuerstein R, Lako M, Xapelli S, Aberdam D, Lagali N. Ocular Surface 2021
  11. Capturing limbal epithelial stem cell population dynamics, signature, and their niche. Altshuler A, Amitai-Lange A, Tarazi N, Dey S, Strinkovsky L, Bhattacharya S, Hadad-Porat S, Nasser N, Imeri J, Ben-David G, Tiosano B, Berkowitz E, Karin N, Savir Y & Shalom-Feuerstein R. Cell Stem Cell 2021 
  12. The role of replication‐removal spatial correlations and cellular replicative lifespan in corneal epithelium homeostasis. Strinkovsky L, Havkin E, Shalom‐Feuerstein R & Savir Y. eLife 2021
  13. SOX2 Regulates P63 and Stem/Progenitor Cell State in the Corneal Epithelium.Stem Cells Cover Bhattacharya S, Serror L, Nir E, Dhiraj D, Altshuler A, Khreish M, Tiosano B, Hasson P, Panman L, Luxenburg C, Aberdam D, Shalom-Feuerstein R. Stem Cells 2019. Selected for the journal’s cover.
  14. RAS Regulates the Transition from Naive to Primed Pluripotent Stem Cells. Altshuler A, Verbuk M, Bhattacharya S, Abramovich I, Haklai R, Hanna JH, Kloog Y, Gottlieb E, Shalom-Feuerstein R. Stem Cell Reports 2018
  15. Corneal-Committed Cells Restore the Stem Cell Pool and Tissue Boundary following Injury. Nasser W, Amitai-Lange A, Soteriou D, Hanna R, Tiosano B, Fuchs Y, Shalom-Feuerstein R. Cell Reports 2018
  16. microRNA-184 Induces a Commitment Switch to Epidermal Differentiation. Nagosa S, Leesch F, Putin D, Bhattacharya S, Altshuler A, Serror L, Amitai-Lange A, Nasser W, Aberdam E, Rouleau M, Tattikota SG, Poy MN, Aberdam D, Shalom-Feuerstein R. Stem Cell Reports 2017
  17. Allele-specific silencing of EEC p63 mutant R304W restores p63 transcriptional activity. F Novelli, A M Lena, E Panatta, W Nasser, R Shalom-Feuerstein, E Candi & G Melino. Cell Death & Disease 2016
  18. A Method for lineage tracing of corneal cells using multi-color fluorescent reporter mice. Amitai‐Lange A, Berkowitz E, Altshuler A, Dbayat N, Suss-Toby E, Tiosano B, Shalom-Feuerstein R. JoVE 2015
  19. Interactions of Melanoma Cells with Distal Keratinocytes Trigger Metastasis via Notch Signaling Inhibition of MITF. Golan T, Messer AR, Amitai-Lange A, Melamed Z, Ohana R, Bell RE, Kapitansky O, Lerman G, Greenberger S, Khaled M, Amar N, Albrengues J, Gaggioli C, Gonen P, Tabach Y, Sprinzak D, Shalom-Feuerstein R,  Levy C. Molecular Cell 2015.
  20. Lineage tracing of stem and progenitor cells of the murine corneal epithelium. Aya Amitai-Lange, Anna Altshuler, Jeffrey Bubley, Noora Dbayat, Beatrice Tiosano, Ruby Shalom-Feuerstein. Stem Cells 2015. Commentary on this paper in this link.
  21. Argonaute2 mediates compensatory expansion of the pancreatic β cell. Tattikota SG, Rathjen T, McAnulty SJ, Wessels HH, Akerman I, van de Bunt M, Hausser J, Esguerra JL, Musahl A, Pandey AK, You X, Chen W, Herrera PL, Johnson PR, O’Carroll D, Eliasson L, Zavolan M, Gloyn AL, Ferrer J, Shalom-Feuerstein R, Aberdam D, Poy MN. Cell Metabolism 2014
  22. Impaired epithelial differentiation of induced pluripotent stem cells from ectodermal dysplasia-related patients is rescued by the small compound APR-246/PRIMA-1MET. Shalom-Feuerstein R, Serror L, Aberdam E, Müller FJ, van Bokhoven H, Wiman KG, Zhou H, Aberdam D, Petit I. Proc Natl Acad Sci U S A. 2013
  23. miR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration. Amelio I, Lena AM, Viticchiè G, Shalom-Feuerstein R, Terrinoni A, Dinsdale D, Russo G, Fortunato C, Bonanno E, Spagnoli LG, Aberdam D, Knight RA, Candi E, Melino G. Journal of Cell Biololgy 2012
  24. Pluripotent stem cell model reveals essential roles for miR-450b-5p and miR-184 in embryonic corneal lineage specification. Shalom-Feuerstein R, Serror L, De La Forest Divonne S, Petit I, Aberdam E, Camargo L, Damour O, Vigouroux C, Solomon A, Gaggioli C, Itskovitz-Eldor J, Ahmad S, Aberdam D. Stem Cells. 2012 M
  25. microRNA-34a regulates neurite outgrowth, spinal morphology, and function. Agostini M, Tucci P, Steinert JR, Shalom-Feuerstein R, Rouleau M, Aberdam D, Forsythe ID, Young KW, Ventura A, Concepcion CP, Han YC, Candi E, Knight RA, Mak TW, Melino G. Proc Natl Acad Sci U S A. 2011
  26. Np63 is an ectodermal gatekeeper of epidermal morphogenesis. Shalom-Feuerstein R, Lena AM, Zhou H, De La Forest Divonne S, Van Bokhoven H, Candi E, Melino G, Aberdam D. Cell Death Differ. 2011 May;18(5):887-96.
  27. miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cell differentiation and control neurite outgrowth in vitro. Chen H, Shalom-Feuerstein R, Riley J, Zhang SD, Tucci P, Agostini M, Aberdam D, Knight RA, Genchi G, Nicotera P, Melino G, Vasa-Nicotera M. Biochemical & Biophysical Research Communications 2010
  28. Skin and corneal cellular therapy using embryonic stem cells: How far are we? Shalom-Feuerstein R, Aberdam D. Expert review in Dermatology 2008 
  29. K-ras nanoclustering is subverted by overexpression of the scaffold protein galectin-3. Shalom-Feuerstein R, Plowman SJ, Rotblat B, Ariotti N, Tian T, Hancock JF, Kloog Y. Cancer Research 2008
  30. miR-203 represses ‘stemness’ by repressing DeltaNp63. Lena AM, Shalom-Feuerstein R, Rivetti di Val Cervo P, Aberdam D, Knight RA, Melino G, Candi E. Cell Death & Differentiation 2008
  31. Galectin-3 regulates RasGRP4-mediated activation of N-Ras and H-Ras. Shalom-Feuerstein R, Levy R, Makovski V, Raz A, Kloog Y. Biochima et Biophysica Acta 2008
  32. Galectin-3 regulates a molecular switch from N-Ras to K-Ras usage in human breast carcinoma cells. Shalom-Feuerstein R, Cooks T, Raz A, Kloog Y. Cancer Research 2005
  33. Restoration of sensitivity to anoikis in Ras-transformed rat intestinal epithelial cells by a Ras inhibitor. Shalom-Feuerstein R, Lindenboim L, Stein R, Cox AD, Kloog Y.  Cell Death & Differentiation 2004

PATENTS

2018 Shalom-Feuerstein R, Yakov-Altshuler A, Verbuk M. Method for isolation, generating or maintenance of naïve pluripotent stem cells using medium containing inhibitors for RAS proteins and/or for RAS downstream effector proteins (U.S. Provisional Patent Application No. 62/613,103).

2011 Shalom-Feuerstein R, Aberdam D, Itskovitz-Eldor J. Methods of generating corneal cells and cell populations comprising same (Extended 20130251692).