Publications

  1. Stem cell responses to stretch and strain. Bhattacharya S, Wolfenson H, Shivdasani R, Shalom-Feuerstein R. Trends Cell Biol. 2021 Nov 17:S0962-8924(21)00209-9. doi: 10.1016/j.tcb.2021.10.007.
  2. Pathophysiology of aniridia-associated keratopathy: Developmental aspects and unanswered questions. Latta L, Figueiredo FC, Ashery-Padan R, Collinson JM, Daniels J, Ferrari S, Szentmáry N, Solá S, Shalom-Feuerstein R, Lako M, Xapelli S, Aberdam D, Lagali N.Ocul Surf. 2021 Oct;22:245-266. doi: 10.1016/j.jtos.2021.09.001.
  3. Soft limbal niche maintains stem cell compartmentalization and function through YAP. Bhattacharya S*,Mukherjee A, Pisano S, Altshuler A, Nasser W, Dey S, Kaganovsky A, Amitai-Lange A, Mimouni M, Socea S, Hasson P, Feral C, Wolfenson H*, Shalom- Feuerstein R*. BioRxiv 2021.05.25.445490.
  4. Capturing limbal epithelial stem cell population dynamics, signature, and their niche. Altshuler A*, Amitai-Lange A*, Tarazi N, Dey S, Strinkovsky L, Bhattacharya S, Hadad-Porat S, Nasser N, Imeri J, Ben-David G, Tiosano B, Berkowitz E, Karin N, Savir Y** & Shalom-Feuerstein R**. Cell Stem Cell. 2021 May; 8:S1934-5909(21)00160-0.
  5. The role of replication‐removal spatial correlations and cellular replicative lifespan in corneal epithelium homeostasis. Strinkovsky L, Havkin E, Shalom‐Feuerstein R & Savir Y. eLife. 2021;10:e56404.
  6. SOX2 Regulates P63 and Stem/Progenitor Cell State in the Corneal Epithelium.Stem Cells Cover Bhattacharya S, Serror L, Nir E, Dhiraj D, Altshuler A, Khreish M, Tiosano B, Hasson P, Panman L, Luxenburg C, Aberdam D, Shalom-Feuerstein R. Stem Cells. 2019 Mar;37(3):417-429. Selected for the journal’s cover.
  7. RAS Regulates the Transition from Naive to Primed Pluripotent Stem Cells. Altshuler A, Verbuk M, Bhattacharya S, Abramovich I, Haklai R, Hanna JH, Kloog Y, Gottlieb E, Shalom-Feuerstein R. Stem Cell Reports. 2018 Mar 13;10(3):1088-1101.
  8. Corneal-Committed Cells Restore the Stem Cell Pool and Tissue Boundary following Injury. Nasser W, Amitai-Lange A, Soteriou D, Hanna R, Tiosano B, Fuchs Y, Shalom-Feuerstein R. Cell Rep. 2018 Jan 9;22(2):323-331.
  9. microRNA-184 Induces a Commitment Switch to Epidermal Differentiation. Nagosa S, Leesch F, Putin D, Bhattacharya S, Altshuler A, Serror L, Amitai-Lange A, Nasser W, Aberdam E, Rouleau M, Tattikota SG, Poy MN, Aberdam D, Shalom-Feuerstein R. Stem Cell Reports. 2017 Dec 12;9(6):1991-2004.
  10. Allele-specific silencing of EEC p63 mutant R304W restores p63 transcriptional activity. F Novelli, A M Lena, E Panatta, W Nasser, R Shalom-Feuerstein, E Candi & G Melino. Cell Death & Disease. 2016. May 19;7:e222.
  11. A Method for lineage tracing of corneal cells using multi-color fluorescent reporter mice. Amitai‐Lange A, Berkowitz E, Altshuler A, Dbayat N, Suss-Toby E, Tiosano B, Shalom-Feuerstein R. JoVE. 2015. Dec 18;(106):e53370.
  12. Interactions of Melanoma Cells with Distal Keratinocytes Trigger Metastasis via Notch Signaling Inhibition of MITF. Golan T, Messer AR, Amitai-Lange A, Melamed Z, Ohana R, Bell RE, Kapitansky O, Lerman G, Greenberger S, Khaled M, Amar N, Albrengues J, Gaggioli C, Gonen P, Tabach Y, Sprinzak D, Shalom-Feuerstein R,  Levy C. Molecular Cell. 2015. Aug 20;59(4):664-76.
  13. Lineage tracing of stem and progenitor cells of the murine corneal epithelium. Aya Amitai-Lange, Anna Altshuler, Jeffrey Bubley, Noora Dbayat, Beatrice Tiosano, Ruby Shalom-Feuerstein. Stem Cells. 2015. Jan;33(1):230-9. Commentary on this paper in this link.
  14. Argonaute2 mediates compensatory expansion of the pancreatic β cell. Tattikota SG, Rathjen T, McAnulty SJ, Wessels HH, Akerman I, van de Bunt M, Hausser J, Esguerra JL, Musahl A, Pandey AK, You X, Chen W, Herrera PL, Johnson PR, O’Carroll D, Eliasson L, Zavolan M, Gloyn AL, Ferrer J, Shalom-Feuerstein R, Aberdam D, Poy MN. Cell Metab. 2014 Jan 7;19(1):122-34.
  15. Impaired epithelial differentiation of induced pluripotent stem cells from ectodermal dysplasia-related patients is rescued by the small compound APR-246/PRIMA-1MET. Shalom-Feuerstein R, Serror L, Aberdam E, Müller FJ, van Bokhoven H, Wiman KG, Zhou H, Aberdam D, Petit I. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2152-6.
  16. miR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration. Amelio I, Lena AM, Viticchiè G, Shalom-Feuerstein R, Terrinoni A, Dinsdale D, Russo G, Fortunato C, Bonanno E, Spagnoli LG, Aberdam D, Knight RA, Candi E, Melino G. J Cell Biol. 2012 Oct 15;199(2):347-63.
  17. Pluripotent stem cell model reveals essential roles for miR-450b-5p and miR-184 in embryonic corneal lineage specification. Shalom-Feuerstein R, Serror L, De La Forest Divonne S, Petit I, Aberdam E, Camargo L, Damour O, Vigouroux C, Solomon A, Gaggioli C, Itskovitz-Eldor J, Ahmad S, Aberdam D. Stem Cells. 2012 May;30(5):898-909.
  18. microRNA-34a regulates neurite outgrowth, spinal morphology, and function. Agostini M, Tucci P, Steinert JR, Shalom-Feuerstein R, Rouleau M, Aberdam D, Forsythe ID, Young KW, Ventura A, Concepcion CP, Han YC, Candi E, Knight RA, Mak TW, Melino G. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52): 21099-104.
  19. Np63 is an ectodermal gatekeeper of epidermal morphogenesis. Shalom-Feuerstein R, Lena AM, Zhou H, De La Forest Divonne S, Van Bokhoven H, Candi E, Melino G, Aberdam D. Cell Death Differ. 2011 May;18(5):887-96.
  20. miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cell differentiation and control neurite outgrowth in vitro. Chen H, Shalom-Feuerstein R, Riley J, Zhang SD, Tucci P, Agostini M, Aberdam D, Knight RA, Genchi G, Nicotera P, Melino G, Vasa-Nicotera M. Biochem Biophys Res Commun. 2010 Apr 16;394(4):921-7. 2010 Mar 15.
  21. Skin and corneal cellular therapy using embryonic stem cells: How far are we? Shalom-Feuerstein R, Aberdam D. Expert review in Dermatology. 2008 June, Vol. 3, No. 3, Pages 357-366.
  22. K-ras nanoclustering is subverted by overexpression of the scaffold protein galectin-3. Shalom-Feuerstein R, Plowman SJ, Rotblat B, Ariotti N, Tian T, Hancock JF, Kloog Y. Cancer Res. 2008 Aug 15;68(16):6608-16.
  23. miR-203 represses ‘stemness’ by repressing DeltaNp63. Lena AM, Shalom-Feuerstein R, Rivetti di Val Cervo P, Aberdam D, Knight RA, Melino G, Candi E. Cell Death Differ. 2008 Jul;15(7):1187-95.
  24. Galectin-3 regulates RasGRP4-mediated activation of N-Ras and H-Ras. Shalom-Feuerstein R, Levy R, Makovski V, Raz A, Kloog Y. Biochim Biophys Acta. 2008 Jun;1783(6):985-93.
  25. Galectin-3 regulates a molecular switch from N-Ras to K-Ras usage in human breast carcinoma cells. Shalom-Feuerstein R, Cooks T, Raz A, Kloog Y. Cancer Res. 2005 Aug 15;65(16): 7292-300.
  26. Restoration of sensitivity to anoikis in Ras-transformed rat intestinal epithelial cells by a Ras inhibitor. Shalom-Feuerstein R, Lindenboim L, Stein R, Cox AD, Kloog Y.  Cell Death Differ. 2004 Feb;11(2):244-7.

PATENTS

2018 Shalom-Feuerstein R, Yakov-Altshuler A, Verbuk M. Method for isolation, generating or maintenance of naïve pluripotent stem cells using medium containing inhibitors for RAS proteins and/or for RAS downstream effector proteins (U.S. Provisional Patent Application No. 62/613,103).

2011 Shalom-Feuerstein R, Aberdam D, Itskovitz-Eldor J. Methods of generating corneal cells and cell populations comprising same (Extended 20130251692).