Lineage tracing of stem and progenitor cells of the murine corneal epithelium. Aya Amitai-Lange, Anna Altshuler, Jeffrey Bubley, Noora Dbayat, Beatrice Tiosano, Ruby Shalom-Feuerstein. Accepted, Stem Cells 2014.  Amitai-Lange_StemCells_2014

Argonaute2 mediates compensatory expansion of the pancreatic β cell. Tattikota SG, Rathjen T, McAnulty SJ, Wessels HH, Akerman I, van de Bunt M, Hausser J, Esguerra JL, Musahl A, Pandey AK, You X, Chen W, Herrera PL, Johnson PR, O’Carroll D, Eliasson L, Zavolan M, Gloyn AL, Ferrer J, Shalom-Feuerstein R, Aberdam D, Poy MN. Cell Metab. 2014 Jan 7;19(1):122-34. Tattikota_Cell_Metabolism_2013

Impaired epithelial differentiation of induced pluripotent stem cells from ectodermal dysplasia-related patients is rescued by the small compound APR-246/PRIMA-1MET. Shalom-Feuerstein R, Serror L, Aberdam E, Müller FJ, van Bokhoven H, Wiman KG, Zhou H, Aberdam D, Petit I. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2152-6. Shalom-Feuerstein_PNAS_2013

miR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration. Amelio I, Lena AM, Viticchiè G, Shalom-Feuerstein R, Terrinoni A, Dinsdale D, Russo G, Fortunato C, Bonanno E, Spagnoli LG, Aberdam D, Knight RA, Candi E, Melino G. J Cell Biol. 2012 Oct 15;199(2):347-63.  Amelio_et al_JCB_2012

Pluripotent stem cell model reveals essential roles for miR-450b-5p and miR-184 in embryonic corneal lineage specification. Shalom-Feuerstein R, Serror L, De La Forest Divonne S, Petit I, Aberdam E, Camargo L, Damour O, Vigouroux C, Solomon A, Gaggioli C, Itskovitz-Eldor J, Ahmad S, Aberdam D. Stem Cells. 2012 May;30(5):898-909. ShalomFeuerstein_StemCells_2012

microRNA-34a regulates neurite outgrowth, spinal morphology, and function. Agostini M, Tucci P, Steinert JR, Shalom-Feuerstein R, Rouleau M, Aberdam D, Forsythe ID, Young KW, Ventura A, Concepcion CP, Han YC, Candi E, Knight RA, Mak TW, Melino G.  Proc Natl Acad Sci U S A. 2011 Dec 27;108(52): 21099-104. Agostini_et al_PNAS_2011

Np63 is an ectodermal gatekeeper of epidermal morphogenesis. Shalom-Feuerstein R, Lena AM, Zhou H, De La Forest Divonne S, Van Bokhoven H, Candi E, Melino G, Aberdam D. Cell Death Differ. 2011 May;18(5):887-96. Shalom-Feuerstein_et al_CDD_2010

miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cell differentiation and control neurite outgrowth in vitro. Chen H, Shalom-Feuerstein R, Riley J, Zhang SD, Tucci P, Agostini M, Aberdam D, Knight RA, Genchi G, Nicotera P, Melino G, Vasa-Nicotera M.  Biochem Biophys Res Commun. 2010 Apr 16;394(4):921-7. 2010 Mar 15. Chen_et al_BBRC_2010

Skin and corneal cellular therapy using embryonic stem cells: How far are we? Shalom-Feuerstein R, Aberdam D. Expert review in Dermatology. 2008 June, Vol. 3, No. 3, Pages 357-366.Shalom-Feuerstein_et al_ExpRevDerm_2008

K-ras nanoclustering is subverted by overexpression of the scaffold protein galectin-3. Shalom-Feuerstein R, Plowman SJ, Rotblat B, Ariotti N, Tian T, Hancock JF, Kloog Y.  Cancer Res. 2008 Aug 15;68(16):6608-16.  Shalom-Feuerstein_et al_CancerRes_2008

miR-203 represses ‘stemness’ by repressing DeltaNp63. Lena AM, Shalom-Feuerstein R, Rivetti di Val Cervo P, Aberdam D, Knight RA, Melino G, Candi E.  Cell Death Differ. 2008 Jul;15(7):1187-95. doi: 10.1038/cdd.2008.69. Epub 2008 May 16. PubMed PMID: 18483491.Lena_et al_CDD_2008

RasGRP4-mediated activation of N-Ras and H-Ras. Shalom-Feuerstein R, Levy R, Makovski V, Raz A, Kloog Y. Galectin-3 regulates  Biochim Biophys Acta. 2008 Jun;1783(6):985-93. Shalom-Feuerstein_et al_BBA_2008
Galectin-3 regulates a molecular switch from N-Ras to K-Ras usage in human breast carcinoma cells. Shalom-Feuerstein R, Cooks T, Raz A, Kloog Y. Cancer Res. 2005 Aug 15;65(16): 7292-300 . Shalom-Feuerstein_et al_CancerRes_2005

Restoration of sensitivity to anoikis in Ras-transformed rat intestinal epithelial cells by a Ras inhibitor. Shalom-Feuerstein R, Lindenboim L, Stein R, Cox AD, Kloog Y. Cell Death Differ. 2004 Feb;11(2):244-7. Shalom-Feuerstein_et al_CDD_2004 


2010  US Provisional Patent Application No. 61/418,915. Methods of generating corneal cells and cell populations comprising same. Production of corneal tissue equivalents from human pluripotent stem cells.